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Thread: Happy Tears?

  1. #1
    Ludicus's Avatar Comes Limitis
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    Default Happy Tears?

    ...where should I post this?
    it’s a small trial so far, the results are so impressive they were published three days ago in The New England Journal of Medicine
    RESULTS
    A total of 12 patients have completed treatment with dostarlimab and have undergone at least 6 months of follow-up. All 12 patients (100%; 95% confidence interval, 74 to 100) had a clinical complete response, with no evidence of tumor on magnetic resonance imaging, 18F-fluorodeoxyglucose–positron-emission tomography, endoscopic evaluation, digital rectal examination, or biopsy. At the time of this report, no patients had received chemoradiotherapy or undergone surgery, and no cases of progression or recurrence had been reported during follow-up (range, 6 to 25 months). No adverse events of grade 3 or higher have been reported.
    A Cancer Trial's Unexpected Result: Remission in Every Patient N. York Times

    Dr. Luis A. Diaz Jr. of Memorial Sloan Kettering Cancer Center, an author of a paper published Sunday in the New England Journal of Medicine describing the results, which were sponsored by the drug company GlaxoSmithKline, said he knew of no other study in which a treatment completely obliterated a cancer in every patient.
    “I believe this is the first time this has happened in the history of cancer,” Dr. Diaz said.
    Dr. Alan P. Venook, a colorectal cancer specialist at the University of California, San Francisco, who was not involved with the study, said he also thought this was a first.
    These rectal cancer patients had faced grueling treatments — chemotherapy, radiation and, most likely, life-altering surgery that could result in bowel, urinary and sexual dysfunction. Some would need colostomy bags.

    They entered the study thinking that, when it was over, they would have to undergo those procedures because no one really expected their tumors to disappear.
    But they got a surprise: No further treatment was necessary.
    “There were a lot of happy tears,” said Dr. Andrea Cercek, an oncologist at Memorial Sloan Kettering Cancer Center and a co-author of the paper, which was presented Sunday at the annual meeting of the American Society of Clinical Oncology.
    Another surprise, Dr. Venook added, was that none of the patients had clinically significant complications.
    Their first patient was Sascha Roth, then 38… two years later, she still does not have a trace of cancer.
    Il y a quelque chose de pire que d'avoir une âme perverse. C’est d'avoir une âme habituée
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  2. #2
    Praeses
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    Default Re: Happy Tears?

    Great news, puts a smile on my face. As I think you pointed out in a thread come years ago there is no "cure for cancer" but there's lots of little cures being developed. IIRC there was one that was a modified AIDS virus that relabelled all the cancer cells so the immune system could burn them out: patients lost kilos of cancer and had to be placed in an induced coma but if they survived, they were cancer free.
    Jatte lambastes Calico Rat

  3. #3
    Sir Adrian's Avatar the Imperishable
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    Default Re: Happy Tears?

    Great news but this is premature. We don't know the long term effects. If it causes remission only for it to come back with a vengeance we are back at square one.
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