Another well-done episode! But with just two little bits of constructive feedback. Firstly, you could have recruited a couple of those amazing Saka or Pointed Hat Riders from Alexandria Escate and Chach to make the inital seleucid attack easier to deal with. The other one being that for your Hellenistic Colonization, I would prefer to have built the military colonies first in Baktria before ANY new minor polis is placed elsewhere as any and all hope of getting any additional colonists after independence is dependent on Baktria getting to that sweet 69% HP required to build the Hellenistic metropolis.
Other than that, good work!
FYI: Since Bukhara is too far to effectively defend, when I played as Baktria, I sacked the place and demolished any structure of value before evacuating the region to concentrate my defenses against the Saka (After making sure that I have the colonists from the completed mission of course

).