I recently had a hard drive crash, and it's no wonder, and was entirely preventable.

When adding and subtracting lots of very large mods, but then dumping them from the drive, or doing this as well with media files, then it's natural to have lots of fragmentation. I've mentioned that before, and once you run a free program to defrag your drive you'll see why it's so jumbled that it's no wonder you have problems. But if you don't run CHKDSK (or whatever is needed on your OS) to look for hard drive errors, then you're only doing half of the routine maintenance.

You may have seen people report a lot of CTDs when you're not seeing any running a mod. Or maybe you're the one reporting them. Realize that not only might you have hard drive errors, but you're probably using hard drive space for virtual memory too, so that might crash it.

Better to schedule an error check in off-time, so when you've finally got some free time to play a marathon of a MTW2 mod, that it's not wasted doing routine hard drive error checking.