US researchers have stumbled upon a compound that may finally lead to a birth control pill for men.
In lab experiments, male mice given the pill were rendered completely infertile during treatment as they produced fewer and less mobile sperm. The drug, originally tested as part of a broader cancer research project, does not affect the hormone system or sex drive, according to the researchers.
"There is no effect on the mouse's mojo. The animals exhibit the normal sexual behaviours and frequency of copulation," says Dr James Bradner of the Dana-Farber Cancer Institute in Boston, whose study appears in the journal
Cell.
What's more, the effect is completely reversible. Once doctors stopped giving the drug to mice, they were able to sire healthy litters, with no apparent side effects, says Bradner.
Scientists say the research is exciting because it applies a unique approach to the problem of male contraception, which is now largely comprised of less reliable methods like condom use, or more permanent procedures like vasectomies.