Research which suggests that patients are more likely to die in hospital if they are admitted at the weekend has been backed up by a major study.
The study, in the Journal of the Royal Society of Medicine, found that patients were 16% more likely to die if they were admitted on a Sunday than mid-week.
The review looked at all admissions to NHS hospitals in England in one year.
The NHS medical director has called for weekend services to be extended.
The research was carried out at University College London and the universities of Birmingham and East Anglia, and covered more than 14 million hospital admissions - both emergency and planned.
The study looked at more than 187,300 patients who died within 30 days of being admitted to hospital during 2009-10.
The researchers found higher death rates if patients went in at the weekend, but a slightly lower death rate if people were already in hospital at the weekend.