Way over my head, but the criticism in a nutshell.
And
recent experiments looking in to the "grainy-ness" of space-time are pointing in the exact opposite direction; a holographic universe would be very "grainy", yet it seems our space-time is much smoother than expected even by standard quantum mechanics.
And like all things nestled in string theory, it requires extra-dimensionality which is as of yet, completely unobserved. It is possible our 3+1 dimensions are just the "shadow" of a higher dimensional universe, but there is no evidence suggesting it.