I wouldn't care.
Knights of Honor was already cartoonish, didn't stop it from being good.
Rome total war was still rather bright and not very historically accurate, Mods fixed that though which no doubt has lead to the grittier realistic version we see today.
The only case where it did annoy me was with The Old Republic because that super deformed stylization is something I associate with The Clone Wars TV Show.. which is

ing terrible! (as are any games that came out of it) lol. The KOTOR style of characters was fine, they should have stuck to that.
I doubt CA would ever do a cartoon game though, now that they're focusing on high end graphics they'd never do it. With that said, I wouldn't mind a cartoon Total War title.