The existence of quale?
The American philosopher Daniel Dennett apparently shows that qualia do not exist, in his thought experiments he shows how the physical systems may be followed through without interruption.
His thought experiments…
http://ase.tufts.edu/cogstud/papers/quinqual.htm
Qualia…
http://en.wikipedia.org/wiki/Qualia
Essentially if you turn the lights off in the brain ~ if you halt neuronal activity, then you stop quale from appearing and perhaps consciousness itself [as this is deemed to be within the context of qualia].
Do you exist and can you make effect in the world…
This is dependent on weather or not consciousness exists which can probably only be resolved within the context of the question; do qualia exist. We must also ask if information exists.
Your interpretations of sensory input changes informations [and quale] which then go out into reality, hence your subjectivity does change real world things.
If quale are a phantasm [unreal] then what is info as experienced in our minds [information proper [not mechanistic info like in a computer]] and what is the quality of redness? They may well be a phantasm in the context that there aren’t specific objects that can be called qualia, but I feel the term is something of a label because we don’t know how to deal with them in terms of physics.





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