not really, when im HRE i normally conquer Venice really fast because it is the only way to get a big enough income to defend your territories and fight multiple fronts and it destroys their chances of attacking your territory, especially Vienna.
Second i move my force upwards and in around 3 turns i have already conquered like 4 settlements...like i said it is the only way to survive....defending with the HRE is just suicide, you have to attack and never let the enemy any chance to counterattack.
Normally after that, depending on the situation i either conquer the polish or the danish or Hungary. but i make sure i conquer at least one to be able to survive when i have multiple fronts. Normally i would never kill any faction because i would want them to confront me with a strong force in the future, but here it is a must. If you leave a nation with even only one settlement then its going to haunt you for the rest of your life....conquer ALL their settlements and destroy the faction forever. These steps are essential in allowing the HRE to remain the power base in Europe.
After this it all depends on the situation but thats really my basic starting expansion with HRE...trust me i've done it millions of times, i should know its one of my fav factions

HRE will never slow down if you do this must it must be swift action and you must command all battles and WIN.
HRE, ironically as it may seem, is the best option because it forces you to think really hard and know that every battle is important while if your the english, even if your determined, you will feel secured and have the opportunity to loose a battle....desperation beats determination.
I would not go on crusades with the HRE, it just divides your forces and wealth even further...resist temptations. And to tell you the truth, alarming as it might seem, conquering rebel settlements are a waste of time and resources, instead focus on Venice and Poland, skipping rebels and leaving them to france, etc.
They will provide a wall and some time and most importantly Venice will always be better then rebels and you will be ridding yourself of multiple fronts in the future....it always works
hope it wasn't too long but it really is the best way to win and it will surely be beneficial for you
