i just played through it all... and everyone in contact with me were at war with me (funny though, portugal offered me an alliance instead of deccing me :/ they were the only ones).
Persia/oman, kazan, sibir, timurids, mali, novgorod, the V guys and their vassals (the biggest faction-bloc in asia after ming/japan was crushed, they were more powerful than ming-japan anyway..) and my own vassals the papal states declared war.
i made only one province gained out the whole thing from the V faction, i accepted all the other's offers of renouncing this and that each time instead because im a merciful person
its satisfying watching 100 infantry regiments appear across europe....
im at like, 1745 or something now so on the home stretch now, then ill do one of my cool map things i did last time (
http://img254.imageshack.us/img254/7715/eu3mapv1xx0.jpg) to show the global reach of the German Eagle
----
Next campaign i was thinking of starting as a small italian faction, and remaking as close as i can; the roman empire.
that or maybe some wierd goal as some other faction of taking every coastal province in the game lawl...