Some minor notes:
Emin Uial need expansion at their northern part towards the "tip" of the lake Evendim
Erebor is missing
There's a ridge that u've forgotten at Eregion, just north of Moria
At Lamedon, you've ommited the Hills that form Tarlang's neck.
Rhudaur and all the lands between the Misty Mts and Greyflood needs some roughing.
Overall, that's some fantastic start you've made