How the hell did ME end up in the Andromeda galaxy when it is a friggin big deal for the Reapers to get anywhere from outside the galaxy? You know, that universe defining arch nemesis that scattered all the advanced tech all over the galaxy and killed everyone that was about to make better tech with it, is billions of years old but can't travel quickly without building Mass relays first?
Also, the Council was very hesitant on opening Mass Relays since the Rachni implying the galaxy still has lots of sectors unexplored... what the hell are people looking for in Andromeda any time soon?
Is this supposed to be concurrent to ME3? If yes, than that's dumb. If no, let's hope they advance the plot far enough to explain this stuff at least to some extent though the base concepts sadly sound like a repetition of ME1 with may be more strategic open world game mechanics. I'm not against that but why call it Mass Effect? What they introduce will be so different it sounds like it may just as well be an independant IP.
Or they want to join the Halo universe. Remnant sounds familiar...