A lot of the problems were associated with what we'd call "communications".
They failed to invent the telegraph!
Important news like the Germans marching across the border could take a while to reach the C-in-C.
The particularly bad days ran from the killing of Severus Alexander to the rise of Claudius Gothicus and Aurelian.
Money is an element in communications and a tonne of silver with a order to get something done is less energy intensive than sending an order with 70 tons of the copper equivalent. The fresh sources of silver and gold which had served the Empire for so long were drying up without replacement.
Aurelian's first act was make sure the debased currency had 5% real silver content.
But maybe Rome's doom came from it's success, Pax Romana created a relative population explosion that reached its height around 200 AD. Too many people to feed and employ for the amount of resources.