Ok, after seeing this for about the 20th time now, in multiple posts on multiple forums, it's pretty clear there's definitely something screwy going on with the Huron.
Playing as GB, my first seige of a Huron settlement, lead to my very first CTD after abuot 30 turns of play. Right after that, all my subsequent game saves were corrupt, and all CRASH to desktop when I try to load a saved game.
I havent tried to go back to my pre Huron interaction, but whats the point really, they're my neighbors and will attack me eventually no matter what I do. If I attack them first I'm in the same boat. Plus it's really not worth playing an "avoid the Huron" campaign, when they're on my borders to the west and south.