I'm experiencing an extremely frustrating situation where the game is freezing during the AI turn phase at the same point. I've run two Grand Campaigns, the first continuously hung at turn 28 during the Huron's AI turn, and the second at turn 31 during the Iriquois.
I have updated to the latest driers tested by CA.
Vista Home Premium 64bit
GTX 280 Superclocked
Q9450 @ 2.66ghz
8GB DDR2 800