Let's match the Seleucids against the Romans. That's right - it's the Beast from the East vs the Best from the West!
THE SELEUCIDS
THE ROMANS (Julii, Brutii, Scipii, SPQR)
Feel free to discuss this matchup from any angle whether it be Campaign, or Multiplayer (low denarii, mid denarii, outrageous denarii) or Single-Player Custom Battle. To avoid any confusion, you might want to specify if you're fighting against a human player or not.